The Miami Project Research Faculty, part of Finding a Cure for Spinal Cord Injury the University of Miami Miller School of Medicine, is a multidisciplinary team of investigators with a common goal - to conduct neuroscience research that addresses traumatic injury to the central nervous system and that ultimately leads to new or improved treatments for spinal cord injury and other neurological disorders. Its research team is made up of basic and clinical scientists with expertise in critical area...
In a state like Lower Saxony, Germany, with a high cattle count, particular importance is attached to applied epidemiology and research into the causes, spread and control of animal diseases. The Hannover Veterinary Institute of the Lower Saxony State Office for Consumer Protection and Food Safety (LAVES) carries out an average 220,000 serological assays each year. In addition the Oldenburg Veterinary Institute of LAVES evaluates a large number of these serological samples. This form of testing...
The Challenge – Affordable Laboratory Management Software for Labs of Any Size While laboratory data management technology has evolved over the past 25 years from simple data collection methods to the current enterprise-level data management and integrated LIMS solutions, too many of the thousands of laboratories around the world are still using manual processes or simple tools like spreadsheets to manage the complexities of laboratory workflow, sample management and data collection. The LIMS...
The Food and Environment Research Agency (Fera) is an executive agency of the UK government’s Department for Environment, Food and Rural Affairs (Defra). It supplies goods and services to public and private sector customers. Fera was founded by bringing together the Central Science Laboratory (CSL), the UK Government Decontamination Service (GDS), the Plant Health and Seeds Inspectorate (PHSI), Plant Variety Rights Office and Seeds Division (PVS) and Plant Health Division (PHD). Fera adopted a...
Drug discovery is perhaps one of the most data sensitive processes in the world. From finding the drug target, to identifying potential drugs, sample validation, concept testing and ultimately launch, data has to be repeatedly logged, revised, checked and analysed in the laboratory. Advances in biotech and genomic technology mean this flow of information is no longer linear; instead, stages of this process are occurring simultaneously, creating a massive data mountain. Laboratory Information Ma...
It has long been recognised that lifestyle factors, environmental factors and physical mental status all have a significant bearing upon human health, implicating that much of what a person is exposed to throughout their life can impact upon their future wellbeing. The Nord-Trøndelag Health Study (HUNT) is striving to develop a clear picture of human health by undertaking a vast medical research initiative to gain invaluable insight into the major causes of the most common diseases. The study w...
Many tests in research laboratories involve substantial logistical and financial efforts. Sophisticated and expensive research materials and equipment are often required. Ideally results are obtained quickly and without error. Therefore the process should be monitored completely. It is not convenient to have to abort an experiment or batch process due to variations in the process parameters because of a lack of monitoring capabilities. For many applications a temperature control unit is an impor...
To be successful, electronic lab notebooks (ELNs) must meet the day-to-day needs of the scientists who use it. This is especially critical for enterprise ELNs designed for use across scientific disciplines. Symyx Notebook is the result of the company?s broad experience developing ELNs for large, global corporations over the course of 15 years. Close collaboration with numerous pharmaceutical companies has been essential in understanding the workflows and use cases encountered by scie...
THE GLOBAL CRO MARKET In today?s life science market, with the strict regulatory framework and ever-increasing drug development costs, establishing strategic partnerships between pharmaceutical and biotechnology companies and CROs has emerged as a critical means to gain and sustain a competitive edge. CROs have become critical contributors to research and development (R&D), clinical trials and manufacturing activities, capable of delivering more volume studies quicker, cheaper and sometimes more...
Recently an innovative partnership was established between one of the worlds major industrial groups, the Swire Group and the UK’s National Oceanography Centre. The Swire Group has long taken a proactive stance on climate change issues, both in terms of measuring and attempting to mitigate the group’s own carbon footprint, and also in its commitment to supporting wider initiatives that aim to tackle this problem.
Part 1 of this article appeared in the January 2008 issue of International Labmate and gave the background to the work carried out by the authors alongside experimental detail and a discussion of some of the Results obtained using the methodology of screening significant factors using the orthogonal array (OA)design. In Part 2 the article discussion centres on the use of Optimisations with the aid of RSM and central composite design,specifically Polynomial mathematical models of retent...
For many organisations, their Laboratory Information Management System (LIMS) is a mission-critical component of their overall corporate Information System (IS) -- whether the company is in a regulated industry such as pharmaceutical manufacturing or in a nonregulated industry such as petrochemicals. LIMS provide the integral connections to these companies? laboratory data, instruments, analysis and reports. Today, LIMS are in the fourth generation of evolution, and many organisations must upgra...
UK Biobank has chosen Nautilus LIMS? from Thermo Fisher Scientific to track, store, manage and report on the biological data of 500,000 people as part of one of the largest medical research projects ever conducted. This implementation is expected to provide immediate benefits with regards to quality of generated results and subsequent scientific advancements.
The Wirral Hospital NHS Trust (WHT) in the northwest of the UK is a busy district general hospital that has one of the country?s most advanced IT hospital environments. Pathology is a prime example where the increasing demand for diagnostic testing within current resources has led to the co-development with Olympus of the dataWizard Instrument Management software system. Last year the laboratories at Wirral Hospital processed 1,873,356 laboratory tests This article looks at the experience of the...
Principal Component Analysis (PCA) is a well-established technique in chemometrics for performing multivariate analyses on spectral and chromatographic data to simplify and clarify the massive amount of data that can result from a typical experiment. The application of this technique has covered many fields such as the evaluation of quality control spectra or characterising control versus treated samples in a metabolomics experiment. However, the use of PCA to analyse and visualise spectral hit...
Those of you who have started your Spanish holiday by sailing on P&O?s ferry the Pride of Bilbao were probably aware of the above deck activities of the Biscay Dolphin Research Programme. This year if you travel on the Ferry you will see for the first time a live TV display of the scientific data being collected below decks by the National Oceanography Centre, (NOC) Southampton. (www/noc.soton.ac.uk) In the ship?s engine room water is being continuously analysed to measure the concentrations of...