Part 1 of this article appeared in the January
2008 issue of International Labmate and gave
the background to the work carried out by the
authors alongside experimental detail and a
discussion of some of the Results obtained using
the methodology of screening significant factors
using the orthogonal array (OA)design. In Part 2
the article discussion centres on the use of
Optimisations with the aid of RSM and central
composite design,specifically Polynomial
mathematical models of retention time and
resolution and Optimisation of separation with
the aid the overlapping contour plot.
Conclusions are then drawn on the results
obtained and presented.
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