‘GREEN CHEMISTRY’ IN THE LABORATORY
By Dr. Andreas Theisen

The term ‘green chemistry’ is commonly used to describe chemical procedures, which meet specific requirements with regards to the conservation of resources and protection of the environment. The objective is to avoid undesired by-products by selecting adequate reaction procedures and media. A typical example is the production of bio fuel,...

ADVANCED BIO-LUMINESCENCE MICROSCOPY
By Esther Ahrent

CLOCKING ON It has been clearly established that a structure in the hypothalamus of the mammalian brain, called the suprachiasmatic nucleus (SCN), contains a ‘daily clock’, which generates near 24 hour (i.e. circadian) rhythmic variations in both physiology and behaviour. This clock is synchronised to changes in environmental illumination (i.e....

DEVELOPMENT OF A TWO PHOTON BURST INTEGRATED FLUORESCENCE LIFETIME SYSTEM FOR SINGLE-PAIR FRET TO ANALYSE INTERACTING PROTEIN POPULATIONS
By Senthila Pathmananthan James Hunt Daniel R. Matthews Andrew J. Beavil Tony Ng Simon M. Ameer-Beg

Fluorescence detection of single molecules represents the ultimate in sensitivity for fluorescence-based assays in biology and medicine by eliminating ensemble-averaging. We describe the development of a time-resolved burst integrated fluorescence lifetime (BiFL) methodology to observe single-molecule dynamics and measure fluorescence lifetime of these molecules as they diffuse through a femtoliter...

Cooling & Freezing Technologies
By Adverts

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SURFACE TOMOGRAPHY AND METROLOGY IN THE QUEST TO UNDERSTAND PREHISTORIC MAN: AN APPLICATION OF LASER SCANNING CONFOCAL MICROSCOPY
By Adrian Evans

A problem restricting the application of lithic microwear analysis to the study of stone tool function in archaeology is the lack of quantitative support for qualitative assessments of different wear traces. Here reflective LSCM is evaluated as a technique for the study of microwear that can potentially resolve this problem....