Rapid Microwave Assisted Organic Synthesis

The Biotage® Initiator+ represents a new generation of instruments for organic, medicinal, materials, nano and polymer chemistry professionals. It is an upgradable and reliable platform for chemists to make great discoveries.

The Initiator+ is a flexible system that utilises all Biotage vials, from 0.2 to 20 mL, in any order or combination, at any time without system modifications, delivering greater flexibility and direct scale-up from milligrams to grams. Initiator+ can also be upgraded with automation solutions to achieve higher throughput to save time and cost.

Features and Advantages

• 300°C reaction temperature
• 30 bar reaction pressure
• In situ temperature measurement
• Upgradable to run peptide synthesis
• Large 10” touchscreen
• Modular automation solutions
• Guided step-by-step Wizard
• Safe and simple

Flexibility
Higher temperatures and pressures of up to 300°C and 30 bar open new possibilities to perform difficult reactions. This allows for more flexibility in choosing a solvent. Even solvents with low boiling points can be run at higher temperatures. Using 'Regulate on pressure' enables the reaction to reach the highest possible temperature during the run. With the addition of the optional fiber optic probe, it is possible to measure the reaction temperature inside the vial for a higher degree of control.

Upgradable
Upgrade from an Initiator+ by connecting the SP Wave peptide synthesis module and the Robot Eight kit to perform microwave assisted peptide synthesis with vortex mixing to ensure homogeneous heat distribution.

Easy to operate
The large touch screen display provides an easy-to-use experience from set-up to results. By using the Biotage Wizard, the user is guided through the set-up of experiments step-by-step. It also includes assistance in converting conventional conditions to microwave synthesis parameters.

Modular
The modular design allows a user to add on different automated sample processors dependent on throughput requirements.

Safe
The reaction vessel is secured with a triple-tier safety lock to ensure maximum operator safety at all times. This in combination with high grade aluminum and a safe explosion box ensures maximum operator safety, even at high temperature and pressure.

Upgrade Path
The Initiator system can be upgraded to an automated 8- or 60-position system. It can also be equipped with the SP Wave Module for an automation solution for peptide chemistry, complete with vortex mixer and liquid handling.

Initiator+ SPWave
The Biotage Initiator+ SP Wave is a programmable synthesizer that can be configured to perform either microwave assisted peptide or organic synthesis.

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