News & Views

Aileron Therapeutics secures $42m for stapled peptide clinical trial


Aileron Therapeutics has secured the second tranche in its series D financing, meaning the overall total has now reached $42 million (£26 million).

This payment followed the successful progression of the company's ALRN-5281 lead Stapled Peptide drug, ALRN-5281, with proceeds from the move set to be directed to the drug's clinical development.

Investors that participated in this latest round of funding included Apple Tree Partners, Excel Venture Management, Lilly Ventures, Novartis, Venture Funds and Roche Venture Fund.

The solution will be used in patients with orphan endocrine disorders and the ALRN-5281 clinical trial will be the first ever to look into Stapled Peptides, which are a new class of drugs that boast a unique set of properties to tackle the key drivers of diseases such as cancer and endocrine/metabolic disorders.

On the other hand, ALRN-5281 is a proprietary, long-acting growth-hormone-releasing agonist, designed to treat endocrine disorders in human cells, such as adult growth hormone deficiency and HIV lipodystrophy.

Joseph A. Yanchik III, president and chief executive officer of Aileron Therapeutics, said: "These proceeds will allow us to advance ALRN-5281 through Phase 1 development and continue to develop our pipeline of Stapled Peptide drugs.

"This is a critical next step for our company, our collaborators and the emerging Stapled Peptide field. We appreciate the continued support of our investors and look forward to sharing more details around our orphan endocrine disorders program when we initiate the Phase 1 study in the coming months."

News of this latest trial comes after a study led by Judy C Boughey, managing director of the Mayo Clinic in Rochester, Minnesota, found that sentinel lymph node (SLN) surgery after chemotherapy can identify nodal status after treatment with neoadjuvant chemotherapy in 84 per cent of node-positive breast cancer patients.

Request more information

You are requesting more details on: Aileron Therapeutics secures $42m for stapled peptide clinical trial.

Your details will be referred to Breaking News and they will provide you with more information regarding this press release themselves. If you have not logged into the website, then please enter your details below.

Contact Details:

* Required fields

top of page Filed under: News & Views

Reader Comments (Total 0 comments)

Post a comment

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.

Post your comment:

top of page