Method Development for the Separation of Therapeutic Proteins (Biopolymers)

Dec 11 2017 - Dec 12 2017

This course gives an extensive training on HPLC (UHPLC) method development for the separation of therapeutic proteins. The fundamentals of reversed-phase (RP), ion-exchange (IEX), hydrophobic interaction (HI) and size-exclusion (SE) chromatography are explained and discussed. Several examples on monoclonal antibodies (mAbs) and related products (such as antibody-drug conjugates /ADCs/) are presented. 

MAbs and related therapeutics currently account for global sales of ≥USD 50 billion and are starting to receive competition from biosimilar incomes. Most pharmaceutical companies have entered the rapidly growing biosimilar market. Therefore, the appropriate and detailed analysis of biopharmaceuticals at different levels (top-down, middle-down and bottom-up) is demanded by the authorities.

Participants will learn the different two- and three-dimensional (3D) optimization models for all the above mentioned chromatographic modes. Fast and efficient method adjustment, transfer and robustness testing are also demonstrated.



+49 30 421 5590
http://molnar-institute.com/services/#training-courses

Digital Edition

Labmate UK & Ireland October / November 2017

November 2017

In this Issue Articles - How to Achieve Ultimate PCR Optimisation Spotlight Features - Incubators, Freezers & Cooling Equipment - Balances & Strain Gauges - Proteomics, Genomics & Mic...

View all digital editions

Events

PEFTEC 2017

Nov 29 2017 Antwerp, Belgium

Saudi International Lab Expo

Dec 04 2017 Riyadh, Saudi Arabia

NepalLab

Dec 14 2017 Katmandu, Nepal

MSACL 2018 US

Jan 21 2018 Palm Springs, CA, USA

View all events