Chromatography

  • Is Sugar Linked to Alzheimer's?

Is Sugar Linked to Alzheimer's?

Feb 08 2018 Read 3043 Times

From obesity to diabetes, it's no secret that a high sugar diet can cause big problems for the human body. Now, researchers have stoked the fire with new evidence suggesting that there could be a link between sugar and Alzheimer's disease.

The new study was published in the journal Diabetologia and fronted by researchers from both the UK and China. It drew on data from over 5000 English Longitudinal Study of Ageing (ELSA) participants and indicated that over the course of a decade, participants with high blood sugar levels suffered from a higher rate of cognitive decline.

“Our study provides evidence to support the association of diabetes with subsequent cognitive decline,” assert the researchers.

The link between HbA1c and cognitive decline

While all participants showed some level of cognitive decline over the 10-year ELSA assessment, it was more pronounced for those with higher HbA1c levels. The term refers to glycated haemoglobin, a common measure of overall blood sugar control that's used to determine if someone has diabetes.

According to the team, the findings "show a linear correlation between circulating HbA1c levels and cognitive decline, regardless of diabetic status."

Is Alzheimer’s a form of "Type 3" diabetes?

As well as being one of the largest studies to link HbA1c levels with cognitive decline, the research also builds on theories that Alzheimer’s disease could be a form of "Type 3" diabetes. In the past other studies have suggested that there could be a "tipping point" which sees a molecular link between blood sugar glucose and Alzheimer’s disease reach critical levels.

In the UK alone Alzheimer's disease affects an estimated 850,000 people. It's the most common type of dementia and causes memory loss, confusion, changes in mood and other side-effects. While the exact cause of Alzheimer's disease is unknown, studies like this continue to build on the knowledge pool and work towards both prevention and cure.

Early intervention

While future studies are still required to pinpoint the long-term benefits of maintaining optimal glucose levels, the team maintain that "interventions that delay diabetes onset, as well as management strategies for blood sugar control, might help alleviate the progression of subsequent cognitive decline over the long-term."

Want to know more about the latest medical breakthroughs? Spotlighting Meadowsweet Filipendula ulmaria, 'Analytical Method Development and Validation for the Identification of Spiraeoside Using RP-HPLC in Pharmaceutical Gel Formulation' aims to validate a Reversed-Phase High Performance Liquid Chromatographic (RP-HPLC) method for the qualitative determination of spiraeoside contained in a gel preparation.

Reader comments

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.

Post a Comment




Digital Edition

International Labmate Buyers' Guide 2019

June 2019

In This Editon Articles - More than One Way to Hit the Bullseye - Gas Chromatography - Vacuum Ultraviolet Spectroscopy - News Bites from the UK Laboratory Industry Mass Spectrometry & Sp...

View all digital editions

Events

Chemspec Europe

Jun 26 2019 Basel, Switzerland

MMC 2019

Jul 01 2019 Manchester, UK

INTERPHEX JAPAN 2019

Jul 03 2019 Tokyo, Japan

PREP 2019

Jul 07 2019 Baltimore, MD, USA

analytica Lab Africa

Jul 09 2019 Johannesburg, South Africa

View all events