Precise Low Temperature Control Improves Reaction Reproducibility
Mar 06 2014 Read 4607 Times
Sygnature Discovery has been using an Asynt DrySyn SnowStorm system to perform low temperature reactions which have traditionally been difficult to undertake reproducibly on a small to medium scale.
The Asynt DrySyn SnowStorm offers an attractive solution to laboratories undertaking low temperature reaction chemistries. Available in a choice of configurations, the DrySyn SnowStorm system provides controlled cooling and heating for sub-ambient parallel chemistry without the need for jacketed reaction vessels, or ice baths. Operating with a suitable chiller / circulator, a DrySyn SnowStorm system provides accurate, stable temperature control down to -50°C and up to +150°C.
Dr Geraint Jones, Associate Director of Chemistry at Sygnature Discovery commented: "Being able to maintain a sub-ambient temperature sometimes for significant periods is really important for reaction reproducibility. The DrySyn SnowStorm connects to an external chiller unit and holds temperatures at a set-point for as long as is required. Setting temperature ramping profiles is also possible which is important in optimisation studies and is a real added benefit to us."
His colleague Mark Mills, Senior Research Chemist at Sygnature Discovery added: "We purchased the DrySyn SnowStorm to achieve tight temperature control (at -20°C) for a reaction involving a stereoselective cyclisation. If we had not been able to maintain this temperature for a sustained period, racemisation could have occurred. We selected this Asynt equipment because it integrated well into our way of working and allowed the use of round-bottomed flasks in a variety of sizes, thereby providing the flexibility to conduct small to medium scale reactions".
Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.
In This Edition Articles - Export experts talk Corona Virus - Automated cell counting shouldn’t cost the earth Laboratory Products - Spectrophotometer Linearity Validation - Analysi...
View all digital editions
May 31 2020 Houston, TX, USA
May 31 2020 Baltimore, MD, USA
Jun 11 2020 Brussels, Belgium
Jun 20 2020 San Diego, CA, USA
Jun 30 2020 Nuremberg, Germany