Laboratory Products

  • Automated Determination of Drugs of Abuse in Hair Samples – Application note

Automated Determination of Drugs of Abuse in Hair Samples – Application note

Jun 06 2018 Read 679 Times

A fully automated sample preparation method has been developed and tested for extraction and analysis of drugs of abuse from hair samples. Performance was tested using hair samples spiked with cannabinoid standards. The automated sample preparation instru-mentation can be directly coupled to any analytical instrumentation for fully automated sample preparation and analysis.

Hair testing is a powerful tool routinely used for the detection of drugs of abuse in forensic and toxicology applications. The analysis of hair can be highly advantageous as it can provide prolonged detection, is non-invasive and provides chronological information about drug intake or chemical exposure, allowing patterns of drug abuse and abstinence to be established, in contrast to the analysis of body fluids. The window of detection is dramatically extended to weeks, months or even years when testing hair, and methods for evading urinalysis do not affect hair analysis.

However, current methodology routinely involves complex and time-consuming washing, homogenization, derivatisation, sample clean-up techniques and extraction techniques before analysis by GC/LC-MS(/MS). This is the driver for the development of automated sample preparation workflows which include direct coupling to the analytical instrumentation, providing fully automated sample preparation and analysis.

Click here to read the full application note.

Reader comments

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.

Post a Comment

Digital Edition

Lab Asia April 2019

April 2019

In This Edition Articles - Mobile Affinity Sorbent Chromatography Of Proteins - Integration of MS and UV Data for Peak Tracking in HPLC Method Development - VMXm takes its First Users 'wher...

View all digital editions



Apr 30 2019 Chicago, IL, USA

Making Pharmaceuticals Exhibition & Conference 2019

Apr 30 2019 Ricoh Arena, Coventry, UK

AOCS Annual Meeting & Expo

May 05 2019 St. Louis, MO, USA

ISCC & GCxGC 2019

May 13 2019 Fort Worth, Tx, USA

ISHM 2019

May 14 2019 Oklahoma, USA

View all events