Laboratory Products

  • Rhabdovirus-free Insect Platform for Viral Vaccines and Gene Therapy Development Announced

Rhabdovirus-free Insect Platform for Viral Vaccines and Gene Therapy Development Announced

Oct 10 2018 Read 581 Times

Merck is collaborating with GlycoBac LLC to offer a Sf-9 insect cell line. GlycoBac’s development of a proven rhabdovirus-negative (RVN) cell line enables Merck to offer the first Sf-9 platform combining a rhabdovirus-free insect cell line with a corresponding, chemically defined cell culture medium. This will be the first non-mammalian cell line in Merck’s cell culture portfolio, allowing customers worldwide access to a safer, high-performing vehicle for recombinant protein expression, Virus-like Particle vaccines and Adeno Associated Virus based gene therapy production.

The insect cell line will provide time and cost savings in analytics and validation, and speed development by circumventing process steps normally required to prove elimination of rhabdovirus. In addition, Merck’s chemically defined hydrolysate-free medium addresses consistency concerns while also reducing overall variability in growth and productivity.

Merck’s insect cell line extends the company’s upstream offerings for viral vaccine and gene therapy applications, complementing Merck’s well-known mammalian CHOZN® platform. Collectively, Merck’s upstream and downstream solutions now constitute a robust portfolio for mAb, vaccine and virus production.

The Merck Sf-RVN platform will be available from a cGMP cell bank to purchase in 2019.

Read comments0

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.


Digital Edition

Lab Asia February 2019

February 2019

In this edition Articles - Detection of molecular markers in aquatic sediments by ion profi les obtained by GC/MS system - Fighting the Resistance: How Rapid Microbial ID with MALDI MS and A...

View all digital editions

Events

BioPharma World Expo 2019

Feb 20 2019 Mumbai, India

Medical Fair India 2019

Feb 21 2019 New Delhi, India

Biotech World

Feb 25 2019 Moscow, Russia

China Lab 2019

Feb 26 2019 Guangzhou, China

SmartLab Exchange

Feb 27 2019 Berlin, Germany

View all events