• State-of-the-Art Effluent Treatment Facility Provides Category II Containment for New National Biologics Manufacturing Centre
    EDS+ Effluent Decontamination System
  • National Biologics Manufacturing Centre in Darlington
  • Operator Interface

Laboratory Products

State-of-the-Art Effluent Treatment Facility Provides Category II Containment for New National Biologics Manufacturing Centre

Mar 30 2016

The Centre for Process Innovation (CPI) has recently completed commissioning of the new £38 million National Biologics Manufacturing Centre in Darlington, Co. Durham, which features a state-of-the-art effluent treatment facility suitable for Containment Level 2 wastes, supplied by Suncombe’s Biowaste Solutions arm.

The new Centre provides companies with open access facilities and expertise to help them develop, prove and commercialise new and improved processes and technologies for biologics manufacture. The facility has a limit of Category II containment. So the waste liquid needs to be collected and thermally denatured prior to discharge to the drain.

The flagship National Biologics Centre is part of the UK Governments Strategy for Life Science, helping UK companies to develop a competitive foothold in the growing global biopharmaceutical market. Biological medicines already account for around 10 – 15% of the current pharmaceutical market and the sector is outperforming the market as a whole. More than one-fifth of new medicines launched on the world market each year are now biotechnology-derived.

The Suncombe equipment is based on its EDS+ Effluent Decontamination System range, with additional features developed to suit the client’s specific requirements. This included Suncombe engineers being part of a team which constructed a 3D model of the proposed Centre, which integrated with the sites overall layout, to allow visualisation of the precise location and position of the treatment facility.

The project scope included the connection of user points (sinks) and a collection sump to the collection pipework, plus the design and modelling of this pipework, in stainless steel from the laboratories to the EDS+ system. It included a number of technical advances, including different user-level login facilities, variable treatment temperatures and times, anti-foam control, pH neutralisation, out-of-hours cooling methodology and 100% positive release for treated waste. Another feature was emergency discharge to a road tanker.

Extensive pre-delivery tests were carried out to ensure that, on delivery to site, the system could be reconnected and ready for operation without any hitches. Factory Acceptance Tests (FATs) included system documentation and certifications reviews, as well as full testing, including automation and dry run simulations, wet testing and system thermal inactivation cycles.

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