• How Does Coffee Compare to Cannabis?

How Does Coffee Compare to Cannabis?

Apr 21 2019 Read 1231 Times

While coffee and cannabis are two very different substances, a new study claims that the two target the same metabolism-influencing neurotransmitters in the brain, though trigger different responses. The findings were published by the Journal of Internal Medicine and suggest that coffee actively binds to the same endogenous chemicals associated with the body's endocannabinoid system, which is usually triggered by smoking or consuming cannabis.

The benefits of cannabis are well-published, with the flowering plant used to regulate the mood, manage chronic pain and treat insomnia. When consumed the drug binds to endocannabinoid system neurotransmitters that deliver messages between the nerve cells and activate the benefits. Now, a team of researchers has discovered that coffee binds to the same neurotransmitters but elicits a different response. While cannabis heightens activity in the body's endocannabinoid system, drinking coffee slows down the system's neurotransmitters.

Chicago researchers discover new endocannabinoid pathways

To investigate the impact of coffee on the human body, a team of Chicago researchers used blood samples to measure more than 700 metabolites from 47 participants over the course of three months. Participants were asked to abstain from drinking coffee during the first month, then progress to four cups a day in the second month and eight cups a day in the third month. The team found that of the 700 metabolites studied, 115 were influenced by drinking coffee.

"These are entirely new pathways by which coffee might affect health," comments Marilyn Cornelis, lead author of the study and researcher at the Northwestern University Feinberg School of Medicine. "Now we want to delve deeper and study how these changes affect the body."

Unraveling the health benefits of coffee

Cornelis muses that excessive consumption of coffee could trigger a decrease in metabolites and suggests the reaction could be a physical adaptation to attempt to rebalance stress levels. She adds that the study could explain why coffee is linked to a host of health benefits, including weight management, glucose-regulating effects and a lowered risk of Type 2 diabetes.

As well as links to the endocannabinoid system, the team found that coffee influences certain metabolites associated with the androsteroid system. This suggests that caffeine could be used to flush steroids from the body, similar to drugs used to treat cancer and other aggressive diseases.

Want to know more about the latest scientific studies concerning cannabis? Don't miss 'Good is Not a Number - Challenges in the Cannabis Extraction Manufacturing: Transitioning from Traditional Subjective to Modern QC/QA/PAT Chromatographic Analysis'.

Reader comments

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.

Post a Comment

Digital Edition

Lab Asia August 2019

August 2019

In this Issue Articles Mass Spectrometry & Spectroscopy 67th ASMS Conference on Mass Spectrometry and Allied Topics Chromatography Using Gas Chromatography for measuring atmo...

View all digital editions


ACS National Meeting & Expo, Fall 2019

Aug 25 2019 San Diego, CA, USA

Microscopy Conference 2019

Sep 01 2019 Berlin, Germany

BMSS Annual Meeting

Sep 03 2019 Manchester, UK

JASIS 2019

Sep 04 2019 Chiba City, Japan

ICMGP 2019

Sep 08 2019 Krakow, Poland

View all events