Chiral

What is Chiral chromatography?
Chiral chromatography is a separation technique used to separate and analyze chiral compounds, which are molecules that exist in two non-superimposable mirror image forms called enantiomers. These enantiomers have identical physical and chemical properties but exhibit different interactions with other chiral molecules, such as those found in biological systems.

In chiral chromatography, the stationary phase is typically a chiral compound or a chiral selector that interacts selectively with one enantiomer over the other. This interaction causes the enantiomers to elute from the chromatographic column at different rates, leading to their separation. Common types of chiral chromatography include normal-phase chiral chromatography, reversed-phase chiral chromatography, and supercritical fluid chromatography.

Chiral chromatography is widely used in various fields such as pharmaceuticals, agrochemicals, food chemistry, and environmental analysis to analyze and separate chiral compounds for research, quality control, and regulatory purposes. It plays a crucial role in drug development and manufacturing, where the separation of enantiomers is essential to ensure the efficacy and safety of pharmaceutical products.


Digital Edition

ILM Guide 2025/26

June 2025

Buyers' Guide Listings- Product Listings by Category- Suppliers Listings (A-Z)Chromatography Articles- Setting the power coefficient and the baseline to linearise the signal of the evaporative ligh...

View all digital editions

Events

AUTOMATICON

Jun 24 2025 Warsaw, Poland

CPhI & P-MEC China 2025

Jun 24 2025 Shanghai, China

Discovery & Development Europe 2025

Jul 01 2025 Basel, Switzerland

MMC 2025

Jul 01 2025 Manchester, UK

analytica Lab Africa

Jul 08 2025 Johannesburg, South Africa

View all events