New Chiral Resolution Screening and Purification Kits

Thermo Fisher Scientific Inc have introduced new Maybridge Chiral Resolution Screening and Purification Kits to give organic chemists simple and rapid access to optically pure chiral compounds from their racemic mixtures. Identifying the best separation conditions under which a target compound can be isolated with optimal yield and purity can take days, or even weeks. The new portfolio of ready-to-use kits reduces development time to just one day, with as little as 0.4mmol of racemate required.

As a commonly used process to obtain optically pure chiral compounds from their racemic mixtures, diastereomeric crystallisation requires careful optimisation of process conditions. Maybridge Chiral Resolution Screening and Purification Kits consist of 384 different combinations of resolving agents and solvents, for both acid and amine-based resolutions, to increase the chances of finding the optimal separation conditions. Cost-effective and convenient, with resolving agents and solvents pre-dispensed in 96-well plates, the kits provide easily identifiable results when screening and simple recovery and purification of enantiomers.

A new educational and informative brochure, downloadable from www.maybridge.com, provides an overview of the key features and benefits of the new Maybridge kits, along with a selection guide. This gives users confidence in the selection of their screening and purification kits, as they can accurately match the kit to the acidity or basicity of their chiral compounds. Furthermore, a brief ‘how it works’ section provides a step-by-step overview of how to use the kits, providing the user with everything they need for successful chiral resolution screening and purification.