• A New Paradigm In High-throughput Preparative Separations


A New Paradigm In High-throughput Preparative Separations

Mar 13 2006

Introduced by Phenomenex, AXIA? is an advanced column packing and hardware design that eliminates bed collapse as a source of failure in short prep columns. Using patented Hydraulic Piston Compression (HPC?) technology, several fundamental problems faced daily by preparative chromatographers have been solved: Collapse, voiding or channeling of the support bed after packing causing premature column failure, Variability in bed density degrading overall reproducibility, Low and/or variable efficiency making scale-up from analytical more difficult, Peak distortion or asymmetry reducing the return on each purification cycle.

With AXIA-packed columns, ideal bed density is custom calculated and automated for each support, chemistry, and column size. Computer control of the entire process assures the proper bed density and uniformity. With a single, controlled hydraulic compression the piston assembly locks in place and detaches; the support media is never allowed to decompress, "relax" or require re-compression, unlike other packing methodologies. The result is an improved, more repeatable packing process, giving Prep chromatographers significant improvements in prep column lifetime (no more premature bed collapse! tested up to 1000+ cycles), with efficiencies and peak symmetries on par with analytical separations. Overall column-to-column consistency is also dramatically improved. Columns are available in 21.2 and 30mm IDs, 50 and 100mm lengths, using high-performance Luna® and Gemini? chemistries. Contact your Phenomenex technical consultant today for more information.

Digital Edition

ILM 49.5 July

July 2024

Chromatography Articles - Understanding PFAS: Analysis and Implications Mass Spectrometry & Spectroscopy Articles - MS detection of Alzheimer’s blood-based biomarkers LIMS - Essent...

View all digital editions


ADLM 2024

Jul 28 2024 San Diego, CA USA

InaLab 2024

Jul 30 2024 Jakarta, Indonesia


Jul 31 2024 Chengdu, China

ACS National Meeting - Fall 2024

Aug 18 2024 Denver, CO, USA


Aug 25 2024 Copenhagen, Denmark

View all events