Double Capacity of IgY Proteome Enrichment Chemistry for Biomarker Discovery
Mar 13 2006
Based on avian-generated antibodies bound to inert microbeads, ProteomeLab IgY-12 liquid chromatography and spin columns selectively partition 12 highly abundant proteins - up to 96 per cent of the protein mass - from human/primate serum or plasma.
Beckman Coulter IgY chemistries offer cleaner capture and broader antigen-binding host range than other capture methods because of the evolutionary distance between chickens and mammals.
"With this advance in column chemistry, we continue to provide the best first step in the biomarker discovery process, increasing its value to the researcher," explained Jerry Feitelson, Ph.D., Manager of Beckman Coulter's Proteomics Business Centre. "Our technology cleanly captures the greatest number of highly abundant proteins with the best available throughput."
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