• Reducing Thermal Stress in Molecular Distillation for Enhanced Product Quality

Laboratory Products

Reducing Thermal Stress in Molecular Distillation for Enhanced Product Quality

Mar 02 2023

Molecular distillation, also called high vacuum wiped film, thin film or short path distillation, is a well-known process to separate thermally sensitive material. Combined in a new unique construction with precise temperature control units, this allows high performance distillation for many different applications and products.

Hybrid construction for versatile and efficient distillation

The SP 1000 CC from Pilodist GmbH is a turnkey system for laboratory use and small scale production. It is optimised to cover a wide range of applications, from high melting to high boiling points and can handle thermally sensitive material with full flexibility and completely continuous operation.

Application cannabis

Beside typical applications like fragrances, (pre-)polymers or reactive chemicals, cannabis is one of the main application areas for the SP 1000 CC, as both short path and molecular distillation are required for optimal results.

In the first pass, the terpenes and light oils are distilled out at a pressure of ~1mbar abs. and an evaporator temperature of ~160°C. This light fraction is condensed at a glass cooling finger at ~30-40°C. Due to the chemical resistant dry running scroll pump, there is no risk of pump oil contamination in this step like in conventional rotary vane pumps of other systems.

The discharged residue fraction will be repassed to distil out the valuable cannabinoids and separate it from the tar-like waste fraction. This step is performed under high vacuum of 1x10-3 to 1x10-5 mbar and temperatures between 140-180°C. The cannabinoids like THC or CBD are condensed at temperatures between 60°C-80°C while the waste fraction with extremely high melting points is discharged tempered up to 200°C.

Due to the fully vacuum tight feed and discharge system, there is no limitation in the charge or receiver vessel size and the system can run in 24/7 operation without any interruption in the vacuum and a throughput up to 7l/h.

More information online

Digital Edition

ILM 49.5 July

July 2024

Chromatography Articles - Understanding PFAS: Analysis and Implications Mass Spectrometry & Spectroscopy Articles - MS detection of Alzheimer’s blood-based biomarkers LIMS - Essent...

View all digital editions


ADLM 2024

Jul 28 2024 San Diego, CA USA

InaLab 2024

Jul 30 2024 Jakarta, Indonesia


Jul 31 2024 Chengdu, China

ACS National Meeting - Fall 2024

Aug 18 2024 Denver, CO, USA


Aug 25 2024 Copenhagen, Denmark

View all events