Microscopy & Microtechniques

THE USE OF HIGH-PRESSURE FREEZING IN CORRELATIVE LIGHT ELECTRON MICROSCOPY

Aug 09 2007

Author: Paul Verkade on behalf of Unassigned Independent Article

Free to read

This article has been unlocked and is ready to read.

Download

With the emergence of Green Fluorescent Protein (GFP) light microscopy has switched from mainly static immuno fluorescence images into imaging very dynamic processes. Dynamic imaging is impossible in the electron microscope but it is excellent for high-resolution studies. Combining both advantages in techniques collectively called Correlative Light Electron Microscopy (CLEM) has gained increasing interest in recent years. New developments within this field include probe development, probe detection, and fixation. Some of these new developments will be discussed and a particular focus will be placed on the fixation process for electron microscopy.

Free to read

This article has been unlocked and is ready to read.

Download


Digital Edition

Lab Asia 31.2 April 2024

April 2024

In This Edition Chromatography Articles - Approaches to troubleshooting an SPE method for the analysis of oligonucleotides (pt i) - High-precision liquid flow processes demand full fluidic c...

View all digital editions

Events

Lab Indonesia

Apr 24 2024 Jakarta, Indonesia

Expomed Eurasia

Apr 25 2024 Istanbul, Turkey

AOCS Annual Meeting & Expo

Apr 28 2024 Montreal, Quebec, Canada

SETAC Europe

May 05 2024 Seville, Spain

InformEx Zone at CPhl North America

May 07 2024 Pennsylvania, PA, USA

View all events