Compound Based Scanning Software Simplifies Multi-Residue Analysis with GC-MS/MS

Designed as ‘the gas chromatographers’ GC-MS system, Bruker’s new SCION TQ™ GC-MS/MS promotes ease of use and increased workflow in busy analytical laboratories. The advantages offered by hardware innovations - reducing the instrument footprint by half but at the same time improving performance over traditional gas chromatography systems - are supplemented by the utility and ease of use of the unique SCION Compound Based Scanning (CBS) software.

Bruker’s software for the SCION TQ includes a number of important tools and features to make method set up, data analysis and comparisons of similar spectra much easier. With gas chromatographers in mind, the SCION software package includes: a CBS Multiple Reaction Monitoring (MRM) compound library for easy set up of methods; additional spectral libraries; plug in to multiple user-customisable spectral libraries with automatic search functions; and Bruker’s mass spectrometry (MS) workstation software. Kefei Wang, Global GCMS Product Manager at Bruker CAM, said: “The software makes complicated analysis easy, particularly for those with little prior mass spectrometry  knowledge. MRM set up requires no expert knowledge - the compound name may be simply dragged from the pre-installed compound library and the software auto-fills the full details of the method and manages the full duty cycle of the triple quad.“ Jim Koers, Bruker CAM Software Manager, added:

“To put this into context, manual TQ method development for a 200 compound method would require around 12,000 keystrokes and take several days. With CBS, we can achieve a fully optimised method in a matter of hours, and with less than 200 keystrokes.”

The SCION TQ system comes complete with the Bruker compound library, which details some 2,500 MRM transitions. Results are  presented in a standard pro-forma accepted across the industry and may be cross-referenced against known spectral libraries to aid interpretation and final delivery.