Chromatography

  • Biopharmaceutical Application Notebook - (U)HPLC Analysis of Biomolecules

Biopharmaceutical Application Notebook - (U)HPLC Analysis of Biomolecules

May 09 2018

Biopharmaceuticals are the fastest growing product segment of the pharmaceutical industry. A thorough characterisation of therapeutic biomolecules is a key task for the successful submission of data for regulatory approvals of new drugs, no matter whether biologic, biosimilar or biobetter.

This application notebook from Tosoh Bioscience compiles more than twenty application notes covering important aspects of biopharmaceutical analysis such as protein aggregation, charge isoforms and glycosylation as well as determination of drug-to-antibody ratio (DAR) of ADCs. The last section of the notebook provides tips and tricks to improve chromatographic separation of biomolecules.


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