Biopharmaceutical Application Notebook - (U)HPLC Analysis of Biomolecules

HPLC

Biopharmaceutical Application Notebook - (U)HPLC Analysis of Biomolecules

09 May, 2018

Published over 8 years ago. See the latest and most current information on HPLC.

Biopharmaceuticals are the fastest growing product segment of the pharmaceutical industry. A thorough characterisation of therapeutic biomolecules is a key task for the successful submission of data for regulatory approvals of new drugs, no matter whether biologic, biosimilar or biobetter.

This application notebook from Tosoh Bioscience compiles more than twenty application notes covering important aspects of biopharmaceutical analysis such as protein aggregation, charge isoforms and glycosylation as well as determination of drug-to-antibody ratio (DAR) of ADCs. The last section of the notebook provides tips and tricks to improve chromatographic separation of biomolecules.

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