• Accelerated photoredox catalysis using high-intensity light source
    Mk I and MkI II Borealis LED Light Sources. (courtesy: Uniqsis)
  • Solstice 12-position batch photoreactor. (courtesy: Uniqsis)

Laboratory Products

Accelerated photoredox catalysis using high-intensity light source

Jan 18 2024

Uniqsis has released an application report showcasing the efficiency of their new high-intensity Borealis™ LED light source in expediting metal-catalysed photoredox reactions. Building upon the Nobel Prize-winning research by Macmillan et al [1], photoredox catalysis has become an important strategy in chemical synthesis. Uniqsis addresses the need for practical, user-friendly benchtop photoreactor systems key to implementing this methodology in laboratories.

The Borealis™ LED light source, available in activation wavelengths ranging from 365nm to 525nm, has proven its efficacy in performing photochemical reactions in both batch and flow modes. Uniqsis has recently introduced a high-intensity variant of the 180W Borealis LED light source. This upgraded version employs high-output LEDs that, surpassing the efficiency of the original Chip-on-Board (COB) LEDs, generate increased light output while maintaining the same power consumption.

The application report focuses on two time-studies conducted in a Uniqsis Solstice 12-position multi-tube batch photoreactor, with the sole variable being the version of the 420nm Borealis LED lamp. In each instance, the LED light source was linked to a 180W Borealis digital power supply. The results highlight how the augmented photon flux delivered by the new 420nm 180W Borealis LED lamp significantly enhances the rate of a metal-mediated photoredox decarboxylative arylation (Macmillan reaction) compared to the original Mk1 version.

Read application report 33 ‘Accelerated Metal-mediated Photocarboxylative Arylation’ in full.

More information online

 1. Prieto Kullmer, C. N., Kautzky, J. A., Krska, S. W., Nowak, T., Dreher, S. D., & MacMillan, D. W. Accelerating reaction generality and mechanistic insight through additive mapping. Science, 376, 532-539 (2022)


Digital Edition

LMUK 49.7 Nov 2024

November 2024

Articles - They’re burning the labs... Spotlight Features - Incubators, Freezers & Cooling Equipment - Pumps, Valves & Liquid Handling - Clinical, Medical & Diagnostic Products News...

View all digital editions

Events

MEDICA 2024

Nov 11 2024 Dusseldorf, Germany

FILTECH

Nov 12 2024 Cologne, Germany

Intech

Nov 12 2024 Tel Aviv, Israel

analytica China

Nov 18 2024 Shanghai, China

Pharma Asia

Nov 20 2024 Karachi, Pakistan

View all events