First Commercial Hybrid Supercritical Fluid/UHPLC System

Agilent Technologies Inc have announced the introduction of the 1260 Infinity Hybrid SFC/UHPLC system. It is the first commercial instrument that performs both supercritical fluid chromatography and ultra high-performance liquid chromatography. This enables intelligent screening for the most suitable method of separation and delivers comprehensive information for complex samples and impurity analysis.

“Now, chromatographers can switch between UHPLC and SFC on the same system without making a single  hardware or method change,” said Stefan Schuette, Agilent Senior Marketing Director, Liquid Chromatography Business. “Users can have great confidence in the results from using these two orthogonal techniques.” The 1260 Infinity Hybrid SFC/UHPLC system delivers LC-like sensitivity over the UHPLC power range. It is the only SFC system providing 600 bar capability. The hybrid system is economical because customers purchase only one instrument to  perform both types of separations. It also conserves valuable bench space. In SFC mode, the instrument uses standard-grade gaseous CO2 for considerable cost savings over SFC-grade CO2. This is in addition to the reduced solvent consumption and waste generation of SFC compared to LC.

Customers also have the option of purchasing just the SFC module as an upgrade to existing 1100, 1200 and 1260 LC systems. The Agilent 1260 Infinity Hybrid SFC/UHPLC system is compatible with Agilent 6100 Series single quadrupole LC/MS systems.