Easy Predictable Scale-up of Liquid Chromatography from Milligrams to Grams to Kilos

Liquid chromatography

Easy Predictable Scale-up of Liquid Chromatography from Milligrams to Grams to Kilos

02 May, 2008

Published over 18 years ago. See the latest and most current information on Liquid chromatography.

Today’s business environment demands all medicinal chemists and separation scientists use their time more effectively and redevelopment of liquid chromatography is time-consuming process.
However, a simple solution is now available – High Performance CounterCurrent Chromatography (HPCCC) instruments. Scale-up on these instruments is simple, taking minutes to work out the conditions for use at either a larger or a smaller scale. Once the HPCCC purification method is developed, usually at the milligram scale, it is simply and easily scaled-up by use of volumetric ratios. This process can be performed in minutes and the results applied very quickly and reliably.
Due to this benefit, Dynamic Extraction’s HPCCC instruments are becoming the first choice amongst separation specialists working in pharmaceutical discovery and development.

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