Enhancing Clinical Diagnostics with Liquid Handling Robot

Zivak Technologies, based in Istanbul, Turkey, relies on Tecan’s Cavro® Omni Robot to automate liquid handling for its clinical diagnostic HPLC and LC–MSMS systems. Mr Avni Çavdar, President of Zivak, explained: “Our Company was approached by several large government hospitals in Turkey that perform a great many organ transplants. Organ recipients are monitored frequently to ensure that they receive the appropriate dose of immunosuppressant drugs, and obtaining rapid, accurate results is crucial. We foresaw a future for the gold standard techniques of HPLC and LC-MS, and decided to develop and manufacture automated LC and LC–MSMS analysers for the clinical diagnostics market.”

“To enable the sample preparation stages to be performed, we needed to integrate a precise and reliable liquid handling system – the Cavro Omni Robot. Combining the Cavro Omni Robot with our technologies enabled us to produce a series of fully automated HPLC and LC-MSMS based analysers that can determine 25-OH metabolites of vitamin D₂ and vitamin D₃, immunosuppressants, amino acids and organic acids in minutes, rather than the hours that may be required for other assay types. The Cavro Omni Robot is very versatile, offering flexible sample handling for up to 180 samples per run, and can accommodate a range of different sample formats, allowing us to integrate a variety of modules. Reliability and accuracy are excellent, and we have demonstrated errors as low as 1%.”