Chromatography

USP Recommends New Ion Chromatography Method for Zinc Oxide Assay

Aug 02 2018 Read 259 Times

USP has updated the General Chapter <591> ‘Zinc Determination’ monograph to include ion chromatography as the preferred method for measuring zinc oxide assay. USP 41–NF 36 was developed in partnership with Metrohm and replaces manual titration methods. The new method is approved by the FDA and benefits users with more ease of use and reliability.

Zinc oxide is used in various skin care creams, drugs, and drug products.

USP has replaced the existing manual titration methods with the ion chromatography method and has rewritten the General Chapter <591>.

The ion chromatography analysis involves separation of zinc oxide followed by post-column reaction using 4-(2-pyridylazo) resorcinol (PAR) reagent and subsequent detection at 530 nm wavelength.
The new method is documented in the Metrohm Application Note AN-U-076, which can be downloaded from the Metrohm website.

The new method is convenient to use and reliable and is approved by the FDA.

Advantages of using Metrohm IC for zinc oxide assay include: precise software-controlled PCR delivery by patented Dosino technology; simple reagent replenishment for easy use; automatic cleaning of the flow path to prevent reagent crystallisation for faster start up and reliability.

Read comments0

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.


Digital Edition

Labmate UK & Ireland July

July 2018

In This Edition Articles - Why Does Nanotechnology Require Mass Spectrometry Spotlight Features Luminescence, UV & Microplate Readers - New Confocal Laser Scanning Microscope Combine...

View all digital editions

Events

ACS National Meeting & Expo

Aug 19 2018 Boston, MA, USA

EuCheMS Chemistry Congress

Aug 26 2018 Liverpool, UK

DioXin 2018

Aug 26 2018 Krakow, Poland

IMSC 2018

Aug 26 2018 Florence, Italy

Medical Fair Asia 2018

Aug 29 2018 Singapore

View all events