Smart column transforms chromatography with in-column monitoring

The ITS Smart Column from Industrial Tomography Systems offers a breakthrough in chromatography by delivering real-time, in-column monitoring through electrical resistance tomography (ERT). Unlike conventional sensors that only measure conditions at the column inlet and outlet, this technology captures detailed data throughout the entire column volume. This provides exceptional visibility into purification processes, resin integrity, and overall process efficiency.

With the Smart Column, users gain real-time insights into column performance, allowing instant visualisation and monitoring. It enables early detection of issues such as resin packing problems and channelling, ensuring consistent resin distribution and reducing the risk of compromised results.

In addition, the Smart Column helps optimise buffer usage, reducing waste and improving process efficiency. It provides precise control over product loading, preventing under- or overloading to maximise resin utilisation. These capabilities contribute to faster process optimisation and accelerated development cycles.

Designed specifically for protein purification, oligonucleotide synthesis, and biopharmaceutical applications, the Smart Column delivers over 1000 in-column measurements, setting a new standard for chromatographic control and process understanding.

More information online