Two New SFC Columns Introduced

Nacalai Tesque introduces 2 new COSMOSIL SFC Columns for Supercritical Fluid Chromatography (SFC).

Supercritical Fluid Chromatography (SFC) has become more attractive because it offers some advantages over HPLC, such as high speed, unique selectivity and environmentally friendly separations. Many conventional normal-phase stationary phases, such as diol, amino and cyano, have been used for SFC applications. However, these phases can be inadequate for certain separations. COSMOSIL 3-Hydroxyphenyl SFC Columns have been especially developed to enhance the capability of SFC separations.

The structural similarities between polar lipids, such as cholesterol and related analogues, have posed chromatographic and spectrometric challenges to analysts interested in quantifying these potential biomarkers. COSMOSIL Quinoline has been developed to improve the separation of these structural isomers by combining the pi-pi interactions and structural rigidity of the COSMOSIL Naphthylethyl phase and the hydrogen bonding of an Ethylpyridine phase.