HPLC
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Zivak Technologies is an international manufacturer company providing solution in the clinical diagnostic field. Zivak Technologies supplies ready to use LC-MS/MS and HPLC analysis kits with its own fully automated sample preparation and injection system which enables laboratories around the globe to make efficient use if their LC-MS/MS instruments as well as HPLC instruments in a fast, accurate and cost efficient way.
There is many scientific studies and papers showing inaccuracy measuring total Vitamin D with commercial immunoassays without separating and measuring Vitamin D2 and Vitamin D3 metabolites individually. ***
HPLC and LC-MS/MS methods are accepted as Gold Method for separate analysis of 25-OH metabolites of Vitamin D. Usage of these chromatographic methods are being increased significantly on clinical laboratories in recent years. Many of these laboratories cannot use their systems effectively due to the fact that these systems require qualified staff, complex sample preparation steps, high kit prices/ operation costs and no availability of walk away systems.
The VD-200 was especially designed for routine Vitamin D2/D3 testing clinical labs. VD-200 enables to analyse Vitamin D2/D3 samples fully automated – without any human intervention- from primer sample tube. Zivak Technologies offers higher sensitivity than entry level LC- MS/MS* by new design Special D detector. This system fully validated with Zivak Vitamin D2/D3 UHPLC Analysis Kit which includes all necessary reagents, calibrator and controls.
Zivak offers a complete solution by VD-200 to clinical laboratories which run their routine Vitamin D2/D3 assays on HPLC-UV and LC-MS/MS systems. “As they have a large number of Vitamin D2/D3 samples, they cannot run all the other LC-MS/MS specific analysis on their LC-MS/MS systems effectively,” said Avni Cavdar, President of Zivak. “We designed the VD-200 especially for these kind of laboratories to provide them a cost- effective solution with a fully automated system and make customer’s expensive LC-MS/MS systems free for specific tests which have to be run on LC-MS/MS system.”
Zivak brings an innovative design on VD-200. Barcode reading, reagent adding, vortex mixing, centrifuge and injection processes can be done by robotic arms. System is not required any human intervention during all steps. By the way, 240 accurate results will be on the desk in 12 hours fully automated.
Key features of VD-200;
*** HPLC Method for 25Hydroxyvitamin D Measurement: Comparison Contemporary Assays Clinical Chemistry 53, No.6, 2006
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