Next generation sample preparation automation

The CambTEK Rapid Extraction System RES is at the cutting edge of fully automated sample preparation of solid dosage forms, in development and quality assurance laboratories, and manufacturing environments. From Phase 1 Development through to Manufacturing Quality Assurance, the RES improves quality of data and increases productivity.

A sample preparation of 500mg paracetamol tablets was carried out using the CambTEK RES. Using automated sample preparation and Mass Spectrometry (MS), a robust, quick and accurate process was envisaged that could be used for content uniformity (CU) analysis of solid dosage forms (SDF). Each sample was analysed by the Microsaic MiD using SIM mode. The resulting data showed excellent linearity from the RES sample preparation and a potential approach to quantitative analysis of API.