Laboratory Products

  • Multi-Parameter Flow Cytometer Delivers High Complexity Cellular Analysis

Multi-Parameter Flow Cytometer Delivers High Complexity Cellular Analysis

Mar 22 2017 Read 733 Times

Beckman Coulter Life Sciences continues to expand the multi-parameter capabilities of its patented CytoFLEX flow cytometer technology. Its latest model, the CytoFLEX LX, with up to six lasers and 21 fluorescent channels, delivers even more parameters with the same exceptional fluorescence sensitivity and superior nanoparticle detection demanded by high end researchers.

With the CytoFLEX LX series, the platform’s innovative excitation and detection capabilities have been further leveraged to meet the high-content needs of researchers interested in up to 23 parameters of cellular analytical measurements.

The ease of use and maintenance of CytoFLEX LX now enables many more researchers to use the system and push their science to this high level. Moreover, other labs which typically used shared lab resources for such complex experiments can now consider accelerating their work with their own benchtop system.

The CytoFLEX sets new standards of fluorescence sensitivity by minimising light loss, so that even dim populations can easily be detected. It can measure as low as ten molecules of fluorescence and measure particles as small as 0.2 micrometers in size.

With the CytoFLEX LX, researchers can measure two scatter parameters in addition to up to 19 fluorescent markers with five lasers; and up to 21 fluorescent markers when six lasers are activated. The patent-pending optical design of the system optimises excitation and light collection efficiency from up to six lasers (375, 405, 488, 561, 638, and 808 nm).

A Wavelength Division Multiplexing (WDM) detection module (also patent-pending) features a bandpass-only design that enables various configurations from four to 21 colours, and contains the full complement of repositionable optical filters.

A new version of Beckman Coulter’s CytoFLEX acquisition software, CytExpert Version 2.0, has also been introduced and is available on the new CytoFLEX LX series. By means of a novel compensation library, users are easily able to set up high colour applications, whether they are in the lab or working remotely.

With CytExpert Version 2.0, researchers can compare and reproduce experimental data over time and across multiple systems, confident that they are reporting accurate and standardised results for each specific application. Other features ideal for high throughput labs include microtitre plate-based analytics; as well as the ability to interface with front-end automation systems. The software also provides tools facilitating compliance with 21CFR11 regulations such as user management, audit trails, and electronic signatures.

Reader comments

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.

Post a Comment




Digital Edition

Lab Asia December 2019

December 2019

In This Edition Mass Spectrometry & Spectroscopy - Translating Proteomic MALDi Tissue Typing to Clinical Pathology - Fusion Protein Complexes Analysed by CG-MALS - Non-equivalent, Multivalen...

View all digital editions

Events

Nepal Lab

Dec 13 2019 Kathmandu, Nepal

SLAS 2020

Jan 25 2020 San Diego, CA, USA

Arab Health

Jan 27 2020 Dubai, UAE

Nano Tech 2020

Jan 29 2020 Tokyo, Japan

HTC-16

Jan 29 2020 Ghent, Belgium

View all events