New Extensive Chip Toolkit Available
Nov 10 2006 Read 1099 Times
ChIP is a powerful technique for studying protein-DNA interactions and can detect the binding of an individual protein to a specific gene sequence in living cells. ChIP assays are used to study histones and non-histone proteins (such as transcription factors) within the cell.
ChIP assays require specific antibodies in order to selectively enrich a chromatin fraction containing a target antigen. The primary antibody must be suitable for immunoprecipitation and the epitope recognised must be available after DNA binding.
Protein-DNA interactions play a crucial role in cellular functions such as signal transduction, transcription, chromosome segregation, DNA replication and recombination, and epigenetic silencing. Identifying the targets of DNA binding proteins and understand the mechanisms of protein-DNA interactions is important for investigating cellular processes.
Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.
In This Edition Mass Spectrometry & Spectroscopy - Translating Proteomic MALDi Tissue Typing to Clinical Pathology - Fusion Protein Complexes Analysed by CG-MALS - Non-equivalent, Multivalen...
View all digital editions
Jan 25 2020 San Diego, CA, USA
Jan 27 2020 Dubai, UAE
Jan 29 2020 Tokyo, Japan
Feb 03 2020 Dubai, UAE
Feb 12 2020 Tokyo, Japan