Biomolecular Interactions Instrumentation Additions

ForteBio®, Inc announced the launch of its Octet RED96 System, as well as its new Dip and Read Protein L Biosensor for use on the company’s Octet platform. The product introductions further widen the scope and utility of the company’s flagship instrumentation system, which provides real-time, label-free analysis of biomolecular interactions, with unprecedented ease of use and cost-efficiency. The Octet RED96 system can rapidly measure protein and other biomolecule concentrations, as well as determine kinetics, affinity and specificity of protein-protein and protein-small  molecule interactions. It extends the capabilities of the company’s premier Octet RED platform by featuring biosensor re-racking, which enables more efficient workflow, reduced amounts of capture molecule use and lower assay-running costs.

ForteBio’s new Dip and Read Protein L biosensor enables rapid and direct quantification of a broad set of kappa light chain containing immunoglobulins, including Fab fragments and single-chain variable fragments otherwise known as ScFv. ForteBio’s Octet platform is based on the company’s proprietary BioLayer Interferometry (BLI) technology, which uses optical biosensors to measure multiple interactions in parallel, without the use of detection agents. The Octet  platform consists of 8- and 16-channel instruments that accommodate 96- and 384-well assay formats. All Octet biosensors are designed to simplify kinetic characterisation and quantitation by eliminating throughput and time-to-result limitations of traditional SPR-based assays and ELISA. The Octet biosensors are disposable, configured in a standard microplate format and are coated with a proprietary biocompatible matrix that is uniform, non-denaturing and has minimal non-specific binding.