Overcoming the challenges of accurate water determination

Any lab that carries out Karl Fischer (KF) titration knows the importance of being able to precisely calibrate its analytical instruments and reagents. The validation process can be performed with pure water but this approach is challenging and its accuracy is therefore dependent on the experience of the user. A Certified Reference Material (CRM) Water Standard provides more accurate and easy-to-use approach, especially for titer determination and the validation and inspection of Karl Fischer titrators in line with ISO, GMP, GLP and FDA guidelines. 

Honeywell’s Hydranal CRMs for both volumetric and coulometric Karl Fischer analysis help ensure that labs have access to the best possible water standards. The Hydranal product line, which was launched more than 35 years ago, has always been produced to the highest possible quality. However, Honeywell’s committed to continuously improving its processes in order to ensure that its products help customers deliver the best quality research results has reaped the ultimate reward. 

The Hydranal range is now produced and certified under ISO Guide 34 in combination with ISO/IEC 17025, the ‘gold standard’ of accreditation, which ensures that researchers can now comply with the strictest regulatory requirements. For ease of use the CRMs are supplied with a printed certificate that contains a certified value, comprehensive documentation, an uncertainty calculation, lot-specific values, expiry date and storage information.

All Hydranal water standards are tested against the NIST (National Institute of Standards and Technology, USA) standard reference material SRM2890, Water Saturated Octanol. Some of the standards are additionally tested against NMIJ (National Metrology Institute of Japan) CRM 4222-a.

All this is further supported by a range of training and expert advice that is available via webinars, presentations and a strong technical team that can help users optimise their Karl Fischer titration and application methods. As a result, Honeywell can quickly help its customers with an array of common issues including:

• How to choose the correct Karl Fischer technique and reagents for different sample types
• How to optimise Karl Fischer titration for specific sample types
• How to use water standards for calibration and to verify sample results

Honeywell can also give advice on more complex issues such as the use of homogenisers, the addition of co-solvents, the application of speciality reagents, how to avoid side reactions in the solvent system and the appropriate use of the Karl Fischer oven. Also, as part of its commitment to provide labs with an exceptional service, Honeywell is currently offering a 15% discount on its Hydranal CRMs range with promo code CRM15. Using high quality CRMs has therefore never been easier or more cost-effective.

Honeywell is justifiably proud of its high service levels and the quality of its products. Its Hydranal CRMs represent best in class technology, which continue to help labs quickly, accurately and consistently implements volumetric and coulometric Karl Fischer titration.

To register now for an account and to take advantage of 15% discount please click here.