Reducing Volume and Time Requirements for Genomic DNA Quantification

Trinean is launching another device that will set the tone in scientific circles: the DropPlate 16 G. This upgrade of the current microfluid disposable, the DropPlate 16 U, allows researchers to quantify 96 DNA/RNA samples of only 2 μl in less than 5 minutes.

Trinean, a spin-off from the University of Ghent and the IMEC research centre, launched their DropSense96 and accompanying DropPlate 16 U on 1 December 2009. The DropPlate 16 U enabled a measuring scope of 5ng up to 3,200ng/μl dsDNA. However, 80% of the principal users of Trinean products analyse genomic DNA, demanding the lowest possible volume requirements for a thorough analysis. In order to meet their needs, Trinean developed a variation of its current chip disposable, specifically for genomic researchers: the DropPlate 16 G (G stands for Genomic).

With the new DropPlate 16 G, volumes of 2μl are sufficient to provide the researcher with a full UV/VIS scan analysis. Not only did it lower the volume requirements, but also the time needed has been reduced by almost 50%: now labs only have to wait 5 minutes before their 96 samples are analysed, whereas it used to be 9. This difference in efficiency is even greater compared to the manual operations one had to perform before the DropSense 96 and DropPlate 16 were in use (typically 45 minutes for 96 samples).

Trinean has already installed over 25 units of this groundbreaking spectrometry system and labs around the world, from academic research centres to pharmaceutical companies, are relying on this state-of-the-art polychromatic plate reader. Integration with existing microplate liquid handlers and robots makes this quantification automatic.