• Revolutionary Technology combines Optical Microscope with Mass Spectrometer 

Mass Spectrometry & Spectroscopy

Revolutionary Technology combines Optical Microscope with Mass Spectrometer 

Oct 09 2014

Shimadzu has released the iMScope TRIO for sale in Europe. The iMScope TRIO revolutionary technology combines an optical microscope together with a mass spectrometer. It is applied to cutting-edge R&D and identifies what users see at the molecular level. iMScope TRIO features extensive functionality for structural analysis through highly accurate MSn analysis.

With three proprietary features (mass spectrometry imaging, integration with optical images, and qualitative analysis), the iMScope TRIO targets applications in life science research organisations, universities, pharmaceutical companies and food as well as manufacturing industries.

Shimadzu is pursuing cooperative research with research agencies to develop more applications for basic research including cancer research and brain function analysis, drug delivery systems (DDS), metabolomics, forensic medicine and lipid analysis. Together with the National Cancer Center in Japan, cutting-edge research results have been obtained that are expected to contribute to ultra-early diagnosis of diseases and drug discovery.

The iMScope TRIO is capable of overlaying observation images from an optical microscope and molecular distribution images obtained by mass spectrometry under atmospheric pressure conditions of ionisation which feature a high resolution of 5 mm or less, the best in the world. This enables detailed analysis of regions of interest, including observation of the lesion area and distribution of anti-cancer drugs.

Enabling high accuracy and precision mass spectrometry, the iMScope TRIO provides high level qualitative analysis via the IT-TOF function, which integrates ion trap (IT) mass spectrometry for MSn analysis with time-of-flight (TOF) mass spectrometry. Not only limited to imaging samples, the system is also capable of analysing samples extracted and separated from tissues via connection with a liquid chromatograph.


Digital Edition

ILM 49.5 July

July 2024

Chromatography Articles - Understanding PFAS: Analysis and Implications Mass Spectrometry & Spectroscopy Articles - MS detection of Alzheimer’s blood-based biomarkers LIMS - Essent...

View all digital editions

Events

ADLM 2024

Jul 28 2024 San Diego, CA USA

InaLab 2024

Jul 30 2024 Jakarta, Indonesia

Miconex

Jul 31 2024 Chengdu, China

ACS National Meeting - Fall 2024

Aug 18 2024 Denver, CO, USA

EMC2024

Aug 25 2024 Copenhagen, Denmark

View all events