Can We Make Artificial Blood?

Apr 01 2017 Comments 0

Blood – it’s a wonderful thing. It makes up approximately 7 percent of your body, with around ten pints in the average human adult. And while some people can’t stand the stuff, it’s hugely important for your body to function properly. There are millions of blood transfusions every day to keep people alive. As a result, doctors need more and more blood donors to come forward and help out. But can we solve the supply problem artificially?

The all-important red stuff

So what is artificial blood? Of course, we’re not talking about the fake blood they have in theatre and film. While red food colouring might look great for stunts, it can’t fulfil the function needed for medical purposes. Instead, scientists are looking at ways of producing red blood cells which make up blood.

Previously, efforts have induced stem cells to form red blood cells. The problem, however, was that this method produced around 50,000 cells each time – nowhere near the huge amount needed for a single transfusion.

Changing the approach

However, in a recent study, researchers at the University of Bristol have made something of a breakthrough. Instead of using stem cells to develop blood cells, they have created immortalised erythroid cell lines that can create the blood cells itself. Once the cell lines are created, using adult stem cells, they can be used to produce red blood cells indefinitely.

It’s also beneficial because it reduces the risk of infection. There is a growing number of diseases and viruses, such as HIV, Hepatitis A, B and C, and Malaria, that can be spread in blood transfusions. “Globally, there is a need for an alternative red cell product,” says Bristol’s Dr Jan Frayne. “Cultured red blood cells have advantages over donor blood, such as reduced risk of infectious disease transmission.”

The only problem with this breakthrough is the price. It costs far more to produce blood in this way than using donations. As a result, initial uses will likely be focussed on the most underrepresented blood types.

Analysing blood's building blocks

As well as supplying blood for transfusions, it’s important for scientists to look at the processes that the body uses to produce blood. Amino acids are one of the building blocks in that process, and they are traditionally analysed using the Moore and Stein method. However, as discussed in ‘Traditional Amino Acid Analysis. What has Changed?’, there is a new era of amino acid analysis which removes some of the traditional difficulties.

Read comments0

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.

Digital Edition

Labmate UK & Ireland October / November 2017

November 2017

In this Issue Articles - How to Achieve Ultimate PCR Optimisation Spotlight Features - Incubators, Freezers & Cooling Equipment - Balances & Strain Gauges - Proteomics, Genomics & Mic...

View all digital editions



Jan 21 2018 Palm Springs, CA, USA


Jan 24 2018 Cardiff, UK

Arab Health

Jan 29 2018 Dubai International Convention & Exhibition Centre

SLAS 2018

Feb 03 2018 San Diego, CA USA


Feb 05 2018 Dubai, UAE

View all events