Chromatography
Published over 16 years ago. See the latest and most current information on Chromatography.
Not all samples may be processed by HPLCMS. In the past unknown substances were then scraped off from the TLC plate, eluted into a tube and transferred in the MS. Now the convenient and universal Camag TLC-MS
Interface is available which semi-automatically extracts zones of interest and directs them online into all common brands of LC-coupled mass spectrometer or extracts them into vials for NMR or (ATR-)FTIR, static nanospray, direct inlet El-MS and MALDI. The interface extracts the complete substance zone with its depth profile and thus allows detections comparable to HPLC down to the pg/zone ranges. The interface has been proven to be one of the most reliable and versatile interfaces for TLC/HPTLC-MS coupling.
ILM 51.5 July 2026