Cogent™ Diamond-Hydride – the “Metabolomics” HPLC Column for Highly Polar Molecules
Sep 06 2017 Read 1001 Times
Cogent™ Diamond-Hydride columns are an ideal choice for metabolomics applications. This unique phase is based on TYPE-C™ silica in which the silica surface is populated with silicon-hydride bonds instead of silanols. Patented bonding technology is used to create the ‘Diamond-Hydride’ with direct silicon-carbon bonds on the silica hydride surface.
Cogent Diamond-Hydride columns are used to retain very polar compounds by aqueous normal phase, but can also operate in normal-phase and reversed-phase modes. The lack of surface silanols leads to fast equilibration times, excellent peak shape and unique retention capabilities for metabolites, underivatised amino acids, carbohydrates and small organic acids.
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