IT Solutions
Accelerate the pace of your research
Nov 07 2017
Chromatographic purification of natural compounds presents many challenges to scientists because of the complex nature of the starting matrices that are used in the process. These starting materials can damage traditional columns and cartridges, decreasing the length of their usage and increasing costs; that is, if the particular system can even accommodate the starting material. Centrifugal partition chromatography (CPC), which uses both liquid stationary and mobile phases, can handle heavily particulated, complex starting materials, such as direct extracts from many biological sources, and has been shown useful for the isolation of piperine from Piper nigrum1 and gingerol from ginger. Additionally, by relying on a liquid stationary phase, traditional columns and cartridges used by preparative HPLC and FLASH methods do not need to be replaced.
CPC is a cost effective alternative for these purification techniques and yields a high quantity of pure compounds. CPC is your ideal solution for natural extract fractionation, natural compound purification, and protein separations.
THE ADVANTAGES OF CPC
• High injection capacity
• No need for pre-treatment prior to injection
• No denaturation of fragile molecules
• No risk of a blocked or contaminated column
BENEFITS OF CPC VS. FLASH AND PREP HPLC
• Purity > 99% and recovery > 95%
• No sample loss • Cost effective - No expensive columns to replace
• Five times less solvent consumption
• High flow rate for low run times
• Easily scalable (milligrams to kilograms)
For further information on CPC please click here.
Digital Edition
ILM 49.5 July
July 2024
Chromatography Articles - Understanding PFAS: Analysis and Implications Mass Spectrometry & Spectroscopy Articles - MS detection of Alzheimer’s blood-based biomarkers LIMS - Essent...
View all digital editions
Events
Jul 28 2024 San Diego, CA USA
Jul 30 2024 Jakarta, Indonesia
Jul 31 2024 Chengdu, China
ACS National Meeting - Fall 2024
Aug 18 2024 Denver, CO, USA
Aug 25 2024 Copenhagen, Denmark