Chiral Screening Service Launched

Phenomenex Inc announced a Chiral Screening Service for customers in pharmaceutical and natural products research and development. This free service provides target screening using a library of HPLC and SFC columns including the Phenomenex Lux™ polysaccharidebased offerings, which demonstrate a success rate approaching 90%. After resolving the chiral compound, Phenomenex also produces method development and optimisation for the service customer, all within 10 business days.

Enantiomers of chiral compounds may have different pharmacological effects in biological systems. Regulations require that enantiomers of all chiral drugs in development be screened separately on their pharmacodynamic and pharmacokinetic properties.

“Resolving chiral compounds is relatively difficult, and column selection can be complicated,” explained Kari Carlson, Brand Manager for Phenomenex. “Our Chiral Screening Service eliminates time-consuming guesswork and also gives customers a chance to ‘test-drive’ our Lux columns.”

The Phenomenex team of chiral experts will customise a plan for each screening project, taking into account specific requirements and overall separation goals. Once a project is completed, the customer will receive a report that details the optimal method including information on the chiral stationary phase (CSP) selected for the separation, running conditions and associated chromatograms.