Advanced chromatography columns for ADC characterisation

Columns

Advanced chromatography columns for ADC characterisation

29 May, 2025

Phenomenex Inc, a global leader in separation science technologies, introduces Biozen™ Native RP-1 and RP-5 - innovative chromatography columns designed for the precise and efficient characterisation of Antibody-Drug Conjugates (ADCs). As ADCs become key players in targeted cancer therapies, these new columns enable reversed-phase separation under native conditions with direct online mass spectrometry (MS) detection.

Featuring proprietary RP-1 and RP-5 particle technology, the columns offer fast, robust native reversed-phase resolution of all Drug to Antibody Ratio (DAR) species, including positional isomers. This advanced design reduces run times and sample handling, delivering higher quality data more efficiently than traditional methods.

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