Streamlining NGS workflows with liquid handling solutions

Innovative liquid handling solutions and magnetic modules from Integra Biosciences are enhancing next-generation sequencing (NGS) workflows by streamlining sample preparation at every stage. These technologies minimise errors, ensure data precision and reliability, and improve laboratory efficiency.

NGS enables rapid sequencing of large volumes of DNA or RNA, supporting applications in genomics, transcriptomics, and personalised medicine. Accurate liquid handling throughout NGS workflows - from sample preparation to library construction, quality control, and sequencing - is crucial for consistent, reproducible results. Manual methods can be time-consuming and prone to errors, impacting data quality.

Automated pipetting systems from Integra Biosciences enhance NGS workflows by accelerating liquid handling and reducing human error. Robots paired with adjustable tip spacing pipettes allow quick, automated sample reformatting from tubes to plates. Handheld electronic pipettes, when integrated with Integra’s magnetic and heating modules, enable semi- or fully automated nucleic acid extractions using magnetic beads.

The MIRO CANVAS microfluidics platform from Integra Biosciences further streamlines NGS library preparation by automating enzymatic fragmentation, PCR, and bead clean-up in a single run, ensuring high accuracy, particularly for long-read sequencing protocols. Additionally, Integra’s pipetting robots and magnetic modules simplify bead clean-up and size selection, while the D-ONE single-channel pipetting module automates critical normalisation and pooling steps before sequencing.

Download the Integra Biosciences workflow chart to see how its advanced liquid handling solutions can elevate NGS library preparation efficiency.

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