• Workhorse System for Routine Analysis Combines Accurate Mass with High Sensitivity

Mass Spectrometry & Spectroscopy

Workhorse System for Routine Analysis Combines Accurate Mass with High Sensitivity

Apr 11 2013

The AB Sciex TripleTOF 4600 System system brings the groundbreaking functionality of TripleTOF technology to routine analysis. TripleTOF technology is considered a leading platform for simultaneous qualitative and quantitative analysis, integrating the highest available sensitivity and speed with high resolution and accurate mass to generate better quality information from every sample.

Increasing complexities of disease research, rising costs of drug discovery and development, and accelerating food contamination crises are among the factors driving the need for a wider range of laboratories worldwide to adopt high-speed, accurate mass-based technology. The TripleTOF 4600 system delivers unparalleled value for a variety of applications, including high-throughput discovery proteomics, food contaminant screening; and routine and comprehensive analysis of drug metabolites in early ADME. It complements the higher-end TripleTOF 5600 system, which was launched in 2010 and has been one of the most quickly and broadly adopted mass spectrometry systems across the world in recent years.

The TripleTOF 4600 system is designed as a highly reliable, workhorse instrument available at a value price, combining the world's fastest acquisition rates with intelligent acquisition strategies to maximise the benefits of UHPLC separations for high resolution accurate mass MS and MS/MS data. By maintaining the core capabilities of the TripleTOF 5600 system, with no compromise in speed, and using sophisticated application-specific software, the TripleTOF 4600 system now makes routine accurate mass quantitative and qualitative analysis available to virtually any laboratory.

To support the expansion of the TripleTOF family of next-generation instruments, AB Sciex has also made available the AB Sciex Accelerated Lab Integration packages, which conveniently combine the TripleTOF 4600 system with application-specific software, Eksigent ekspertTM UHPLC systems, reagents, training and service & support. The ALI packages for drug metabolism studies, food safety testing, lipid profiling, discovery proteomics, protein quantitation and biologics are designed to simplify the adoption of TripleTOF technology for laboratories that have never used LC/MS/MS or want to quickly and easily upgrade from older-generation technology.

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