High-Performance LC Triple Quadrupole Mass Spectrometers Launched

At the 2012 Japan Analytical Scientific Instruments Show (JASIS), Bruker today launches two game-changing LC-triple quadrupole (LC-TQ) mass spectrometers, the high-performance EVOQ Qube™ and the ultra-high sensitivity EVOQ Elite, which are setting new standards for analytical performance and quantitative robustness. The EVOQ series is targeted at LC-TQ performance leadership and delivers major advances in robustness, ease of method developments and productivity.

The EVOQ LC-TQ systems introduced today incorporate Bruker’s new Advance™ UHPLC systems. In addition, the EVOQ platform features several major innovations: the industry’s first Vacuum-Insulated Probe (VIP) heated electrospray technology preserves and ionises thermally fragile molecules with outstanding sensitivity; the Active Exhaust atmospheric pressure ionisation source with a robust orifice vacuum interface significantly enhances quantitative robustness for difficult samples; the novel, ‘flat-tuning’, proprietary Interlaced Quadrupole Dual Funnel (IQ-DF™) maximises sensitivity; novel PACERTM software enables ‘exception based data-review’, a revolutionary feature that significantly reduces the error rate for quantitative analysis.

Bruker’s patented lens-free triple-quad mass filter design, which enhances MRM performance, is standard on all EVOQ systems, making the EVOQ LC-TQ inherently easier to use and maintain. Other high-performance TQ features include Bruker’s unique Compound Based Scanning (CBS) technology, the novel VIP heated-ESI and APCI ion sources, fast 14,000 amu/sec scan speed and 25 milliseconds positive/negative ion switching, all for leading-edge TQ performance and analytical power.

Collin D’Silva, Bruker CAM Division President, said: “Our customers need to run more samples, spend less time cleaning and re-tuning instruments, and use software to minimise errors associated with the daily review of thousands of chromatograms. The EVOQ with PACER software delivers significant value to a laboratory whose core focus is providing time-sensitive quantitative data.”

The Advance HPLC, UHPLC, and the UHPLC-OLE products offer ultra-low dead-volume which enables excellent reproducibility at analytical flow-rates, an integrated column-oven, and bench-space savings. Paired with the industry workhorse CTC auto-sampler, the Advance LC portfolio delivers precision and accuracy required for sustained, high-sensitivity LC-MRM quantitative analysis.