New Worthington animal free bioprocessing enzymes & collagenase sampling program

Reagents

New Worthington animal free bioprocessing enzymes & collagenase sampling program

04 Mar, 2026

Worthington has announced two new products for nucleic acid research and bioprocessing applications; NUCxyme™ DNA/RNA Nuclease, Recombinant, Animal Free and Ribonuclease U2, Animal Free.

Animal Free Collagenases, Types AFA, AFB and AFC, and STEMxyme® STZ1, and STZ2 collagenase/neutral protease blends are derived from cultures grown in medium completely devoid of animal-based components and designed for bioprocessing applications where introduction of potential animal derived pathogens must be prevented. Levels of secondary proteases are similar to Types 1 and 2 collagenase.

  • CLSAFA is the original animal free grade designed to have collagenase and secondary proteases similar to Types 1 collagenase
  • CLSAFB contains higher collagenase and caseinase activities than CLSAFA
  • CLSAFC has especially low tryptic activity similar to Type 4 collagenase
  • CLSAFD contains two-to-three-fold higher specific activity than CLSAFA
  • Purified collagenase, code CLSAFP contains minimal secondary proteolytic activities along with high collagenase activity
  • STZ1 & STZ2, 0.22μ filtered STEMxyme® AF Collagenase/Neutral Protease (Dispase®) blends for primary and stem cell isolation

Worthington also offers a collagenase sampling program. Under the program, individual researchers are provided with 100 mg samples of up to three different lots or types of collagenase for evaluation in their own applications.

For further details international customers should check Worthington’s International Distributor listing for a distributor. If you do not have a Worthington Distributor for your country, please contact International Sales.

More information online

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