The Need for Specific Detectors in Nitrosamine Testing in Water

Chromatography

The Need for Specific Detectors in Nitrosamine Testing in Water

31 Oct, 2012

Published over 13 years ago. See the latest and most current information on Chromatography.

Dr Mark Landon, Andrew James and Phillip James
1 min read
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Nitrosamines are a group of compounds pertaining to the generalised formula R1N(-R2)-N=O where R1 and R2 can be a vast array of hydrocarbon based

compounds, with over 300 known and investigated. Of these, at least 90% are known or thought to be carcinogenic, with n-nitrosodimethylamine

(NDMA) the most widely investigated and thought to be the most dangerous to health. Nitrosamines are formed in a wide range of industrial processes,

food and beverage production, as well as formation within the human stomach. Although many different mechanisms for the production of these

compounds are known, generally heat combined with an amine and a nitrate/nitrite source is the most common.

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