Chromatography
Maximising Core-Shell Performance on Conventional HPLC Systems
Jul 09 2012
Author: Jeff Layne and Simon Lomas on behalf of Phenomenex Inc
In order to fully realise the performance potential of core-shell columns on conventional HPLC systems, some simple system optimisations maybe necessary to minimise extra-column band broadening effects. In this report, a series of simple measures (adjusting detector acquisition rate; optimising connective tubing; use of a low-volume flow cell) are made to a standard HPLC system in order to achieve UHPLC-comparable performance with sub-3μm core-shell media.
Digital Edition
Lab Asia 31.2 April 2024
April 2024
In This Edition Chromatography Articles - Approaches to troubleshooting an SPE method for the analysis of oligonucleotides (pt i) - High-precision liquid flow processes demand full fluidic c...
View all digital editions
Events
Apr 28 2024 Montreal, Quebec, Canada
May 05 2024 Seville, Spain
InformEx Zone at CPhl North America
May 07 2024 Pennsylvania, PA, USA
May 14 2024 Oklahoma City, OK, USA
May 15 2024 Birmingham, UK
