Mass Spectrometry & Spectroscopy
Electron-Induced Dissociation of Anions
Sep 03 2012
Author: Aruna S. Prakash, Eleanor J. Humphrey and Jackie A. Mosely on behalf of Unassigned Independent Article
Tandem mass spectrometry (MS/MS) has become an integral part of chemical analysis within many industries due to its ability to identify known or unknown compounds, often at low abundance, and on a rapid time-scale that is compatible with chromatography. A recent addition to this tandem MS tool-box is a technique called Electron-Induced Dissociation (EID)1. An extension of Electron-Capture Dissociation (ECD) which uses low energy electrons to fragment multiply charged cations [2] and Electron Detachment Dissociation (EDD) for multiply charged anions [3], EID is the dissociation of singly charged ions following irradiation with electrons of slightly greater energy than used for ECD. This stems from the very early work by Cody et al. who brought forth the benefit of Electron Impact Excitation of Ions from Organics (EIEIO) [4].
Digital Edition
Lab Asia 31.2 April 2024
April 2024
In This Edition Chromatography Articles - Approaches to troubleshooting an SPE method for the analysis of oligonucleotides (pt i) - High-precision liquid flow processes demand full fluidic c...
View all digital editions
Events
Apr 22 2024 Marrakech, Morroco
Making Pharmaceuticals Exhibition & Conference
Apr 23 2024 Coventry, UK
Apr 23 2024 Kintex, South Korea
Apr 23 2024 Seoul, South Korea
Apr 24 2024 Jakarta, Indonesia