Mass Spectrometry & Spectroscopy

Electron-Induced Dissociation of Anions

Sep 03 2012

Author: Aruna S. Prakash, Eleanor J. Humphrey and Jackie A. Mosely on behalf of Unassigned Independent Article

Free to read

This article has been unlocked and is ready to read.


Tandem mass spectrometry (MS/MS) has become an integral part of chemical analysis within many industries due to its ability to identify known or unknown compounds, often at low abundance, and on a rapid time-scale that is compatible with chromatography.  A recent addition to this tandem MS tool-box is a technique called Electron-Induced Dissociation (EID)1.  An extension of Electron-Capture Dissociation (ECD) which uses low energy electrons to fragment multiply charged cations [2] and Electron Detachment Dissociation (EDD) for multiply charged anions [3], EID is the dissociation of singly charged ions following irradiation with electrons of slightly greater energy than used for ECD.  This stems from the very early work by Cody et al. who brought forth the benefit of Electron Impact Excitation of Ions from Organics (EIEIO) [4].

Free to read

This article has been unlocked and is ready to read.


Digital Edition

Lab Asia 29.6 Dec

November 2022

In This Edition Chromatography Optimising Viral Vector Purification Strategies with Multimodal Chromatography Key UHPLC Characteristics Required for High throughput LC-MS New Low Volum...

View all digital editions


CPhI & P-MEC China 2022 - NEW DATES

Dec 20 2022 Shanghai, China & Online 21 November 2022 to 13 January 2023

Smart Factory Expo 2023

Jan 25 2023 Tokyo, Japan

Arab Health

Jan 30 2023 Dubai, UAE

Nano Tech 2023

Feb 01 2023 Tokyo, Japan

Medlab Middle East

Feb 06 2023 Dubai, UAE

View all events