Expanded miRNA Microarray Catalogue

Agilent Technologies, Inc recently introduced three new microRNA
microarray designs: Human miRNA Microarray v2.0, Mouse miRNA
Microarray v1.0 and Rat miRNA Microarray v1.0. All are based on the
Sanger Institute`s miRBase 10.1, updated in December 2007. The
updated Human miRNA Microarray v2.0 contains 723 human and 76
human viral probe sets. Viral miRNAs are increasingly associated with
some cancers, so Agilent included these probe sets to provide
additional value for cancer researchers.
The new Mouse miRNA Microarray v1.0 contains all known mouse
and mouse gamma herpes virus miRNAs. There are 567 mouse and 10
mouse gamma herpes virus distinct probe sets. The new Rat miRNA
Microarray v1.0 contains all 350 known rat miRNA probe sets. Agilent
launched the first comprehensive microarray system for expression
profiling of human miRNAs in April 2007, and it has been positively
received by the research community.
The Agilent miRNA microarray platform`s limit of detection is less than
1 attomole with a dynamic range of five orders of magnitude. Probe
specificity and the unique labelling procedure discriminates individual
miRNAs. Agilent`s novel method for efficiently labelling miRNA in total
RNA eliminates tedious size fractionation and requires only 100
nanograms of input RNA from precious samples.
The Agilent miRNA assays are delivered as eight 15K arrays per
standard 1in. x 3in. glass slide. The Human v2.0 kit, Mouse v1.0 kit
and Rat v1.0 kit are each available as two different pack sizes: one
slide with eight arrays or three slides with 24 arrays. The human,
mouse and rat miRNA assays are also available as individual slides,
each containing eight microarrays. This helps users tailor purchases to
their research requirements.